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example_arguments.txt

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    example_arguments.txt 1.51 KiB 
    # MHC I single allele frequencies
python hogvax.py --k 170 --outdir mhcI_unlinked --population World --peptides ../OptiVax_Data/Peptides/optivax_unlinked_mhc1_4512_filtered_peptides.pep --allele-frequencies ../OptiVax_Data/Frequencies/IEDB_population_frequency2392_normalized.pkl --ba-threshold 0.638 --binding-affinities ../OptiVax_Data/BindingAffinities/25June_mhc1_netmhc-4.1_pred_affinity_pivot.pkl.gz --min-hits 1 --verbose 1

# MHC I haplotypye frequencies
python hogvax.py --k 174 --outdir mhc1_robust --population White Black Asians --peptides ../OptiVax_Data/Peptides/optivax_unlinked_mhc1_4512_filtered_peptides.pep -af ../OptiVax_Data/Frequencies/haplotype_frequency_marry.pkl -t 0.638 -ba ../OptiVax_Data/BindingAffinities/all_mhc1_predictions_for_haplotypes.pkl.gz --min-hits 1

# MHC II single allele frequencies
python hogvax.py --k 322 --outdir mhc2_unlinked --population World --peptides ../OptiVax_Data/Peptides/optivax_unlinked_mhc2_37435_filtered_peptides.pep -af ../OptiVax_Data/Frequencies/IEDB_population_frequency_mhc2_275normalized.pkl -t 0.638 -ba ../OptiVax_Data/BindingAffinities/25June_mhc2_netmhcii-4.1_pred_affinity_pivot_v1v2.pkl.gz --min-hits 1

# MHC II haplotype frequencies
python hogvax.py --k 324 --outdir mhc2_robust --population White Black Asians --peptides ../OptiVax_Data/Peptides/optivax_unlinked_mhc2_haplotype_37435_filtered_peptides.pep -af .../OptiVax_Data/Frequencies/haplotype_frequency_marry2.pkl -t 0.638 -ba ../OptiVax_Data/BindingAffinities/all_mhc2_predictions_for_haplotypes.pkl.gz --min-hits 1