R Interface to C API of IBM ILOG CPLEX, depends on IBM ILOG CPLEX (>= 12.1)
R Interface to C API of COIN-OR Clp, depends on COIN-OR Clp Version >= 1.12.0
sybil - Efficient Constrained Based Modelling in R
R Interface to C API of GLPK, needs GLPK Version >= 4.42
SBML (Systems Biology Markup Language) integration in sybil
Gurobi support for sybil